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Accelerator based epithermal neutron source for neutron capture therapy

Authors: Brugger, R.; Kunze, J.;

Accelerator based epithermal neutron source for neutron capture therapy

Abstract

Several investigators have suggested that a charged particle accelerator with light element reactions might be able to produce enough epithermal neutrons to be useful in Neutron Capture Therapy. The reaction choice so far has been the Li(p,n) reaction with protons up to 2.5 MeV. A moderator around the target would reduce the faster neutrons down to the epithermal energy region. The goals of the present research are: identify better reactions; improve the moderators; and find better combinations of 1 and 2. The target is to achieve, at the patient location, an epithermal neutron current of greater than 10{sup 9}n/cm{sup 2}sec, with a dose to tissue from the neutrons alone of less than 10{sup {minus}10} rads/n and a dose from the gamma rays in the beam of less than 10{sup {minus}10} rads/n.

Country
United States
Related Organizations
Keywords

43 Particle Accelerators, Nucleon Reactions, Design, 73 Nuclear Physics And Radiation Physics, Hadrons, 663450 -- Heavy-Ion-Induced Reactions & Scattering-- (1992-), Lithium 7 Target, Hadron Reactions, 430301 -- Particle Accelerators-- Ion Sources, Epithermal Neutrons, Baryons, Nuclear Reactions, Fermions, Tritium Target, Nucleons, Triton Reactions, Neutrons, Charged-Particle Reactions, Progress Report, Radiotherapy, Targets, Radiation Sources, Neutron Capture Therapy, Neutron Therapy, Document Types, Therapy 550603* -- Medicine-- External Radiation In Therapy-- (1980-), 663430 -- Nucleon-Induced Reactions & Scattering-- (1992-), Hydrogen 1 Target, Particle Sources, Neutron Sources, Medicine, Baryon Reactions, Nuclear Medicine, 62 Radiology And Nuclear Medicine, Radiology, Elementary Particles, Accelerators, Proton Reactions

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average