This paper presents a deterministic uncertainty analysis (DUA) method for calculating uncertainties that has the potential to significantly reduce the number of computer runs compared to conventional statistical analysis. The method is based upon the availability of derivative and sensitivity data such as that calculated using the well known direct or adjoint sensitivity analysis techniques. Formation of response surfaces using derivative data and the propagation of input probability distributions are discussed relative to their role in the DUA method. A sample problem that models the flow of water through a borehole is used as a basis to compare the cumulative distribution function of the flow rate as calculated by the standard statistical methods and the DUA method. Propogation of uncertainties by the DUA method is compared for ten cases in which the number of reference model runs was varied from one to ten. The DUA method gives a more accurate representation of the true cumulative distribution of the flow rate based upon as few as two model executions compared to fifty model executions using a statistical approach. 16 refs., 4 figs., 5 tabs.