The Center for Accelerator Mass Spectrometry (CAMS) in the Earth and Environmental Sciences Directorate at Lawrence Livermore National Laboratory (LLNL) operates two accelerators and is in the process of installing two new additional accelerators in support of a variety of basic and applied measurement programs. To monitor the radiation environment in the facility in which these accelerators are located and to terminate accelerator operations if predetermined radiation levels are exceeded, an updated computer controlled radiation monitoring system has been installed. This new system also monitors various machine safety interlocks and again terminates accelerator operations if machine interlocks are broken. This new system replaces an older system that was originally installed in 1988. This paper describes the updated B190 computer controlled radiation monitoring and safety interlock system.