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Nuclear medicine and imaging research (quantitative studies in radiopharmaceutical science). Progress report, January 1, 1992--December 31, 1992

Authors: Cooper, M.; Beck, R. N.;

Nuclear medicine and imaging research (quantitative studies in radiopharmaceutical science). Progress report, January 1, 1992--December 31, 1992

Abstract

This report describes three studies aimed at using radiolabeled pharmaceuticals to explore brain function and anatomy. The first section describes the chemical preparation of [F18]fluorinated benzamides (dopamine D-2 receptor tracers), [F18]fluorinated benzazepines (dopamine D-1 receptor tracers), and tissue distribution of [F18]-fluoxetine (serotonin reuptake site tracer). The second section relates pharmacological and behavioral studies of amphetamines. The third section reports on progress made with processing of brain images from CT, MRI and PET/SPECT with regards to brain metabolism of glucose during mental tasks.

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United States
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Keywords

400703, 551001, Dopamine, 610, 38 Radiation Chemistry, Unsealed Radionuclides In Diagnostics, Cerebellum, Receptors, Labelling, 616, Chemical Preparation, Tissue Distribution, Cerebrum, 59 Basic Biological Sciences, Cerebral Cortex, Behavior, Radiochemistry, 550101, Progress Report, Fluorine 18, Structure-Activity Relationships, Radioisotope Production, Amides, Rats, Spiperone, Man, Sympatholytics, Radiopharmaceuticals, Liquid Column Chromatography 550601, 62 Radiology And Nuclear Medicine, And Nuclear Chemistry, Tracer Techniques

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
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