
doi: 10.2152/jmi.56.381
pmid: 20224232
)bythe patch clamp technique. Therefore, thapsigargin-induced SOCE is a useful approach to investigatemechanisms of SOCE.Immortal NIH3T3 cells have been establishedfrom the embryonic NIH Swiss mice fibroblasts. TheNIH-3T3 cell is a useful cell line for investigationof transformation, stress fiber formation, or feedercells of keratinocytes. NIH-3T3 cells have epidermalgrowth factor (EGF) receptors (2), fibroblast growthfactor (FGF) receptors (3), platelet derived growthfactor (PDGF) receptors (3), bombesin receptors(3) bradykinin receptors (4) and ATP receptors(5), all of those receptors require calcium influx.Stimulation of those receptors mobilizes stored Ca
Membrane Glycoproteins, ORAI1 Protein, Biological Transport, Fibroblasts, Cell Line, store operated calcium entry, Mice, NIH-3T3 cells, inhibitors, NIH 3T3 Cells, Animals, Calcium, Calcium Channels, Calcium Signaling, Stromal Interaction Molecule 1, Stromal Interaction Molecule 2
Membrane Glycoproteins, ORAI1 Protein, Biological Transport, Fibroblasts, Cell Line, store operated calcium entry, Mice, NIH-3T3 cells, inhibitors, NIH 3T3 Cells, Animals, Calcium, Calcium Channels, Calcium Signaling, Stromal Interaction Molecule 1, Stromal Interaction Molecule 2
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