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Vascular Health and Risk Management
Article . 2013 . Peer-reviewed
License: CC BY NC
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Vascular Health and Risk Management
Article
License: CC BY NC
Data sources: UnpayWall
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Vascular Health and Risk Management
Article . 2013
Data sources: Europe PubMed Central
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PubMed Central
Conference object . 2013
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Dove Medical Press
Review . 2013 . Peer-reviewed
Data sources: Dove Medical Press
https://dx.doi.org/10.2147/vhr...
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Endoglin: a critical mediator of cardiovascular health

descriptionPublicationkeyboard_double_arrow_right Article , Conference object , Review 01 May 2013 English Publisher:Informa UK LimitedJournal:Vascular Health and Risk Management (eissn: 1178-2048, Copyright policy )
Authors: Kapur,Navin K; Morine,Kevin J; Letarte,Michelle;

doi: 10.2147/vhrm.s29144

pmid: 23662065

pmc: PMC3647444

Endoglin: a critical mediator of cardiovascular health

Abstract

Endoglin (CD105) is a type III auxiliary receptor for the transforming growth factor beta (TGFβ) superfamily. Several lines of evidence suggest that endoglin plays a critical role in maintaining cardiovascular homeostasis. Seemingly disparate disease conditions, including hereditary hemorrhagic telangiectasia, pre-eclampsia, and cardiac fibrosis, have now been associated with endoglin. Given the central role of the TGFβ superfamily in multiple disease conditions, this review provides a detailed update on endoglin as an evolving therapeutic target in the management of cardiovascular disease.

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Keywords

Male, Ventricular Remodeling, Endoglin, Receptors, Cell Surface, Review, Ligands, Cardiovascular System, Vascular Health and Risk Management, Pre-Eclampsia, Antigens, CD, Cardiovascular Diseases, Pregnancy, Transforming Growth Factor beta, Animals, Homeostasis, Humans, Female, Telangiectasia, Hereditary Hemorrhagic, Signal Transduction

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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 45
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
45
Top 10%
Top 10%
Top 10%
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gold
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