The pharmacology and therapeutic potential of (-)-huperzine A

descriptionPublicationkeyboard_double_arrow_right Article , Conference object , Review , Other literature type 01 Sep 2012 English Publisher:Informa UK LimitedJournal:Journal of Experimental Pharmacology (eissn: 1179-1454,

Copyright policy )

Authors: Herzon, Seth; Tun,Maung Kyaw Moe;

doi: 10.2147/jep.s27084

pmid: 27186124

pmc: PMC4863551

The pharmacology and therapeutic potential of (-)-huperzine A

- Summary
- Subjects
- Metrics

Abstract

(-)-Huperzine A (1) is an alkaloid isolated from a Chinese club moss. Due to its potent neuroprotective activities, it has been investigated as a candidate for the treatment of neurodegenerative diseases, including Alzheimer's disease. In this review, we will discuss the pharmacology and therapeutic potential of (-)-huperzine A (1). Synthetic studies of (-)-huperzine A (1) aimed at enabling its development as a pharmaceutical will be described.

Related Organizations

Yale University
United States
University of New Haven
United States
Department of Chemistry Yale University
United States

Keywords

Journal of Experimental Pharmacology, Review

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	19
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%