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International Journal of Women's Health
Article . 2012 . Peer-reviewed
License: CC BY NC
Data sources: Crossref
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International Journal of Women's Health
Article
License: CC BY NC
Data sources: UnpayWall
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PubMed Central
Other literature type . 2012
Data sources: PubMed Central
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Vaginal rings for delivery of HIV microbicides

Authors: Malcolm, R Karl; Fetherston, Susan M; McCoy, Clare F; Boyd, Peter; Major, Ian;

Vaginal rings for delivery of HIV microbicides

Abstract

Following the successful development of long-acting steroid-releasing vaginal ring devices for the treatment of menopausal symptoms and contraception, there is now considerable interest in applying similar devices to the controlled release of microbicides against HIV. In this review article, the vaginal ring concept is first considered within the wider context of the early advances in controlled-release technology, before describing the various types of ring device available today. The remainder of the article highlights the key developments in HIV microbicide-releasing vaginal rings, with a particular focus on the dapivirine ring that is presently in late-stage clinical testing.

Country
United Kingdom
Related Organizations
Keywords

dapivirine, /dk/atira/pure/subjectarea/asjc/2700/2730; name=Oncology, antiretroviral, 610, Review, /dk/atira/pure/subjectarea/asjc/2700/2729, SILCS diaphragm, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being; name=SDG 3 - Good Health and Well-being, sustained release, thermoplastic, /dk/atira/pure/subjectarea/asjc/2900/2913; name=Maternity and Midwifery, name=Obstetrics and Gynaecology, name=Oncology, Gynecology and obstetrics, name=Maternity and Midwifery, name=SDG 3 - Good Health and Well-being, /dk/atira/pure/subjectarea/asjc/2700/2729; name=Obstetrics and Gynaecology, /dk/atira/pure/subjectarea/asjc/2700/2730, /dk/atira/pure/subjectarea/asjc/2900/2913, RG1-991, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, controlled release, silicone elastomer

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    79
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 1%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
79
Top 10%
Top 10%
Top 1%
Green
gold