Muayad AliManufacturing Department, Australian Red Cross Blood Service, Dandenong, VIC, Australia I have read with great interest the article "Epidemiology of dengue: past, present and future prospects" by Murray et al.1 Dengue viruses are usually transmitted by Aedes mosquitoes, which are highly sensitive to environmental conditions. Temperature, rainfall, and humidity are critical to mosquito survival and reproduction; the higher temperatures minimize the required time for virus replication and dissemination in the mosquito.2 I accept that dengue will increase in the future as the article outlines, as climate change will contribute to a substantial increase in the number of people, and the proportion of the global population at risk of dengue fever.3View original paper by Murray et al.