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Acrodermatitis Continua of Hallopeau Evolving into Generalized Pustular Psoriasis Following COVID‐19: A Case Report of a Successful Treatment with Infliximab in Combination with Acitretin

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type , Report 01 Apr 2021 English Publisher:Informa UK LimitedJournal:Biologics: Targets and Therapy, volume Volume 15, pages 107-113 (eissn: 1177-5491,

Authors: Dominik Samotij; Ewelina Gawron; Justyna Szczęch; Elżbieta Ostańska; Adam Reich;

doi: 10.2147/btt.s302164

pmid: 33948082

pmc: PMC8088410

Acrodermatitis Continua of Hallopeau Evolving into Generalized Pustular Psoriasis Following COVID‐19: A Case Report of a Successful Treatment with Infliximab in Combination with Acitretin

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Abstract

The global pandemic of coronavirus disease 2019 (COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is emerging. Various cutaneous manifestations have been observed in patients with SARS-CoV-2 infection, yet exacerbations of psoriasis have been reported sporadically. Acrodermatitis continua of Hallopeau (ACH) is an uncommon, sterile pustular dermatosis involving one or more digits. In some rare cases, ACH may evolve into generalized pustular psoriasis (GPP), which is a severe, and potentially life-threatening, form of psoriasis that manifests itself with widespread eruptions of pustules. We describe the first case of a patient in whom ACH abruptly progressed into GPP during COVID-19. A combination of infliximab and acitretin was used allowing swift clinical improvement.

Related Organizations

Rzeszów University
Poland

Keywords

sars-cov-2, Medicine (General), R5-920, pustular psoriasis, coronavirus, Targets and Therapy [Biologics], biologics, Case Report, psoriasis, biologic therapy

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