Signal Transduction by Type I Interferons
Copyright policy )Signal Transduction by Type I Interferons
The two classes of interferons, type I (IFNalpha, IFNbeta, IFNomega, and IFNtau) and type II (IFNgamma) are pleiotropic cytokines that exhibit antiviral, antiproliferative, and immunomodulatory effects on their target cells. This article summarizes the advances made in elucidating the molecular events that mediate the biological responses to type I interferons.
- Moores Cancer Center United States
- University of California, San Diego United States
- University of California, San Diego United States
Transcription, Genetic, QH301-705.5, Active Transport, Cell Nucleus, NF-kappa B, Membrane Proteins, Receptor, Interferon alpha-beta, Protein-Tyrosine Kinases, Methylation, Models, Biological, DNA-Binding Proteins, Enzyme Activation, Gene Expression Regulation, Interferon Type I, Trans-Activators, Animals, Humans, Biology (General), Phosphorylation, Protein Processing, Post-Translational, Receptors, Interferon, Signal Transduction
Transcription, Genetic, QH301-705.5, Active Transport, Cell Nucleus, NF-kappa B, Membrane Proteins, Receptor, Interferon alpha-beta, Protein-Tyrosine Kinases, Methylation, Models, Biological, DNA-Binding Proteins, Enzyme Activation, Gene Expression Regulation, Interferon Type I, Trans-Activators, Animals, Humans, Biology (General), Phosphorylation, Protein Processing, Post-Translational, Receptors, Interferon, Signal Transduction
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