Comparison of different probe-level analysis techniques for oligonucleotide microarrays
Copyright policy )Comparison of different probe-level analysis techniques for oligonucleotide microarrays
Three different software packages for the probe-level analysis of high-density oligonucleotide microarray data were compared using an experiment-derived data set that was validated using real-time PCR. The efficiency with which these three programs could identify true positives in this data set was assessed. In addition, estimates of false-positive and false-negative rates were determined. The performance of the programs using very small data sets was also compared, and recommendations for use are suggested.
- Stony Brook University United States
QH301-705.5, Gene Expression Profiling, Myocardium, Polymerase Chain Reaction, Rats, Animals, False Positive Reactions, Biology (General), Oligonucleotide Probes, False Negative Reactions, Oligonucleotide Array Sequence Analysis
QH301-705.5, Gene Expression Profiling, Myocardium, Polymerase Chain Reaction, Rats, Animals, False Positive Reactions, Biology (General), Oligonucleotide Probes, False Negative Reactions, Oligonucleotide Array Sequence Analysis
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