Climate change is creating serious challenges for Malaysia’s agricultural sector, with unpredictable weather patterns, droughts, and floods undermining food production and threatening national food security. Climate-Smart Agriculture (CSA) offers an effective response by integrating sustainable practices that increase productivity, enhance climate resilience and reduce greenhouse gas emissions. This study employs a qualitative methodology to examine the adoption of CSA practices among Malaysian farmers and to propose strategic solutions using the Quintuple Helix Model. The findings identify five key CSA practices currently in use: soil conservation in hilly areas, agroforestry in lowland regions, climate-resilient crop varieties, organic farming and precision agriculture technologies. However, the overall adoption level among Malaysia farmers is still low due to high implementation costs, reluctance to change, a lack of understanding and erratic weather. This study emphasised on the Quintuple Helix model in order to promote CSA adoption by focusing on the necessities policies, funding, capacity-building initiatives and stakeholder cooperation. Malaysia can attain sustainable food security and meet its 2050 carbon neutrality targets by removing these obstacles. For a thorough grasp of CSA's socioeconomic effects, future studies should investigate quantitative insights and broaden their attention to additional locations.