Hydrogen blending in natural gas (NG) is in active use and expanding as a decarbonization approach for residential uses, and while existing research has investigated the safety for a variety of residential appliances operating on hydrogen-blended natural gas (HBNG), the operability impact of HBNG use on natural gas clothes dryers (NGCD) remains under-characterized. A standard size LG NGCD was used across three dry load masses (2, 4, and 6 kg) and four fuel blends (0, 20, 40, and 50 v/v% H2) to study the impacts of HBNG use upon NGCD performance. Drying curves were fit with a decreasing-sigmoid form to extract drying behaviours and predict drying time based upon test conditions. These results informed an empirical regression of sigmoidal parameters which was then compared with an adapted numerical model that captures dynamic heat and mass transfer processes in the dryer system. Drying time was found to monotonically increase with hydrogen content in NG, with the largest penalty relative to pure NG operation observed at 2 kg and 50% H2 (Δt=4.95 minutes; 23.15% increase). Both predictive models reproduced measured drying times accurately for the set of test conditions assessed, with the empirical correlation having an R2 = 0.973 and RMSE = 2.00 minutes, and the numerical model having an R2 = 0.987 and RMSE = 1.32 minutes. All test cycles remained below the 80-minute ENERGY STAR test cycle time limit, reinforcing that clothes dryers can operate acceptably on HBNG up to 50% hydrogen with moderate increases in drying time.