Aim: This review explores advanced strategies of water contamination mitigation by integrated chemical and ecological solutions, assessing their efficiency in surface and groundwater treatment of harmful pollutants such as bromides and chlorides. The study aims to assess the value of these integrated approaches and their potentials to ensuring water quality improvement and increased protection of public health. Study Design: This study involves a review of literature on combined chemical treatment and ecological methods of water body contamination that takes into account the period from 2019 through 2024. The literature shows the efficacy and limitations of the integrated strategy in various environmental perspectives. Methodology: The research was based on a comprehensive literature review from databases such as Google Scholar, PubMed, Scopus, and Web of Science. It focused on those studies that assessed the application of chemical methods like advanced oxidation processes and nanomaterials along with ecological solutions such as constructed wetlands and phytoremediation. Results: This review identified 12 relevant studies concerning the successful integration of chemical and ecological strategies in mitigating water contamination. This study points to some of the key findings which include the synergy between the chemical methods, advanced oxidation processes for fast contaminant degradation, and ecological solutions such as phytoremediation, which ensures the long-term sustainability of such approach. These integrated systems have been efficient in treating pollutants like bromides, chlorides, and heavy metals, besides observing remarkable improvements in water quality. Conclusions: Integrated chemical and ecological approaches are highly effective in addressing water contamination challenges. These strategies not only provide immediate improvements in water quality but also offer long-term environmental sustainability. However, issues such as cost, scalability, and the need for specialized monitoring systems remain significant challenges. Further research is needed to optimize these systems and to explore their applicability in varying geographical and economic contexts.