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Polymers and Polymer Composites
Article . 2025 . Peer-reviewed
License: CC BY NC
Data sources: Crossref
https://doi.org/10.2139/ssrn.5...
Article . 2024 . Peer-reviewed
Data sources: Crossref
https://doi.org/10.2139/ssrn.5...
Article . 2024 . Peer-reviewed
Data sources: Crossref
https://doi.org/10.2139/ssrn.5...
Article . 2024 . Peer-reviewed
Data sources: Crossref
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3d Printed Pegda-Hydroxyapatite Composite Scaffolds for Bone Regeneration

Authors: Liana Mkhitaryan; Lilit Baghdasaryan; Zaruhi Karabekian; Seda Gasparyan; Miguel A. Rodríguez; Marina Aghayan; Viktorya Rstakyan;

3d Printed Pegda-Hydroxyapatite Composite Scaffolds for Bone Regeneration

Abstract

This study presents manufacturing of Poly(ethylene glycol) diacrylate (PEGDA)- Hydroxyapatite (HA) composite by Digital Light Processing (DLP) technology. PEGDA along with HA extracted from bovine was mixed with a photoinitiator (PI) and water to achieve optimized rheology for DLP. The printing parameters for DLP were optimized. Chemical composition, microstructure and mechanical properties of the composite were characterized. The compressive strength of PEGDA-HA composite achieved a maximum of 20 MPa in Z direction. The flexural strength was 56 MPa and 34 MPa for horizontal and vertical orientations, correspondingly, indicating anisotropic behavior of the samples. The cytotoxicity assessments were performed. The 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT) assay and confocal imaging indicated that the scaffold powder exhibits minimal cytotoxicity at low concentrations (0.001 g/ml), with high cell viability and minimal cell death or membrane damage.

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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    2
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Top 10%
Average
Average
gold