Canada's National Pollutant Release Inventory (NPRI) is part of a global network of over 50 national Pollutant Release and Transfer Registries. These registries track industrial pollutant releases into the air, water, and land, and transfer and disposal of pollutants to various waste management practices. Despite the NPRI being a long-standing public dataset that can speak directly to Canadian progress on various reductions in chemical releases and waste generation sought by the United Nations' Sustainable Development Goal (SDG) 12, its data on pollutant transfers and disposals is so far overlooked in tracking SDG progress. This study aims to uncover the potential of this waste-related data to provide meaningful measures of progress toward SDG 12 using two case studies (on the Basel Convention on the Control of Transboundary Movements of Hazardous Wastes and their Disposal and the Minamata Convention on Mercury) and a framework by the Organization for Economic Cooperation and Development to do so. The findings challenge the premise that progress in the current SDG 12.4 indicator (number of parties to international chemical agreements that transmit required information) also leads to progress on overall SDG 12.4 waste-related aims. This analysis sets a precedent for using publicly available PRTR data from any country to monitor progress toward SDG 12 waste-related objectives, opening up new possibilities for more accurate global tracking of this SDG.