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Photodiagnosis and Photodynamic Therapy
Article . 2025 . Peer-reviewed
License: CC BY
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https://doi.org/10.2139/ssrn.4...
Article . 2024 . Peer-reviewed
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https://doi.org/10.2139/ssrn.5...
Article . 2025 . Peer-reviewed
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Enhanced Glaucoma Detection Using U-Net and U-Net+ Architectures Using Deep Learning Techniques

Authors: B.P. Pradeep kumar; Pramod K.B. Rangaiah; Robin Augustine;

Enhanced Glaucoma Detection Using U-Net and U-Net+ Architectures Using Deep Learning Techniques

Abstract

This study compares multiple image processing and deep learning methods to demonstrate an enhanced approach to glaucoma diagnosis. The approach focuses on noise reduction using median filtering and optic disc segmentation utilizing the U-Net and U-Net+ architectures. Capsule Networks were utilized for feature extraction and Extreme Learning Machines (ELM) for diagnostic classification. Three datasets were evaluated, including DRISHTI-GS, DRIONS-DB, and HRF, utilizing important parameters such as accuracy, sensitivity, and specificity. The findings revealed that median filtering reduced noise by 97.88%, with a peak signal-to-noise ratio of 44.99. U-Net beat U-Net+ in optic disc in the process of segmentation with a Dice coefficient of 0.8557, a Jaccard index of 0.7307, and higher segmentation accuracy. The suggested model has great diagnostic accuracy, scoring 99% for DRISHTI-GS, 99.5% for DRIONS-DB, and 98.5% for HRF. These findings show that using deep learning approaches can increase glaucoma diagnosis accuracy and reliability, with important implications for healthcare applications and patient outcomes.

Keywords

DRIONS-DB, Medicine (General), Optic Disk, Reproducibility of Results, Glaucoma, Signal-To-Noise Ratio, Sensitivity and Specificity, Frame networks, Retinal intra-ocular region, R5-920, Deep Learning, Image Interpretation, Computer-Assisted, Image Processing, Computer-Assisted, Humans, U-NET layers, DRISHTI-GS

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    7
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
7
Top 10%
Average
Top 10%
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