The investigation along the Coromandel coastline of South-east India focused on assessing microplastics abundance using Simpson's diversity index (DIMP), Degradation-carbonyl index (DgCIMP), Pollution load index (PLIMP) and Ecological risk fraction (RfMP). These indices evaluated the dissemination and transportation of MPs across a 1076 km stretch divided into five zones from Chennai to Kanyakumari. During the wet season, average microplastics abundance (101 ± 36.6 items/kg dw) was lower compared to the dry season (143 ± 56.2 items/kg dw). Notably, 54% and 45% of microplastics were found in the 0.1-0.5 mm size range, with 45% and 64% being colored microplastics, and 80% and 71% being fibers during the wet and dry seasons respectively. Micro-Fourier-transform infrared spectroscopy (μFTIR) analysis showed rayon (34%) and PE (64%) dominance in ports and estuaries during both seasons. Kottaipattinam Port exhibited higher diversity indices (DIMPsh=0.56,DIMPsz=0.66,DIMPco=0.50andDIMPpo=0.65) compared to other zones, with an overall diversity index IDIMP of 0.57. Notably, among the DgCIMP values (n = 96), only 12 fell within the moderate photo-chemical oxidation range (0.16-0.35), while the majority (n = 60) surpassed 0.35 indicating higher oxidation levels, with some (n = 24) exceeding 0.50, signifying extreme oxidation. PLIMP revealed that 42% of sampling stations had very low to negligible MP contamination levels in ports and estuaries. However, ecological risk fraction RfMP values ranged from 10.2 to 13,670, with 27% of values exceeding 1500, indicating higher coastal ecological risk in 13 sampling stations.