Pattern formation, arising from systems of autonomous reaction-diffusion equations, on networks has become a common topic of study in the scientific literature. In this work we focus primarily on directed networks. Although some work prior has been done to understand how patterns arise on directed networks, these works have restricted their attentions to networks for whom the Laplacian matrix (corresponding to the network) is diagonalizable. Here, we address the question "how does one detect pattern formation if the Laplacian matrix is not diagonalizable?" To this end, we find it is useful to also address the related problem of pattern formation arising from systems of reaction-diffusion equations with non-local (global) reaction kinetics. These results are then generalized to include non-autonomous systems as well as temporal networks, i.e., networks whose topology is allowed to change in time.