This paper intends to establish conceptual foundations of analyzing the economic dimensions of regional or global emerging and endemic infectious disease events such as the case of 2019-nCoV. The 2019-nCoV Global Economic Impact Simulator (the 2019-nCoV-GEI-Simulator) attempts to identify the 2019-nCoV transmission parameters and forecast its trajectories. The model introduces seven basic indicators - (i) the 2019-nCoV contagious spread intensity rate (SI), (ii) the treatment level for 2019-nCoV infected cases rate (T); (iii) the number of 2019-nCoV causalities rate (-C); (iv) the economic wear from the 2019-nCoV epidemic rate (-Π); (v) the 2019-nCoV contagious cases multiplier rate (M); (vi) the total economic leaking from the 2019-nCoV epidemic rate (-Ltotal); and (vii) the economic desgrowth from the 2019-nCoV epidemic rate (-δ2019-nCoV). This specific simulator investigates the 2019-nCoV epidemic final impact on the Chinese economy domestically and internationally.