The current international system is characterized by a large number of states and other non-state actors acting in International Relations. In conjunction with increasing the number of states, on the international level, interdependence between actors is increased. This study aims to elaborate Multilateral Diplomacy, as one of the most appropriate forms of multilateral cooperation among states to solve some global problems affecting two or more states such as is security and economic development. Also, this work presents the strengths and weaknesses of this form of interstate activity. Although this work will present a critical approach to this form of diplomacy, as of tightened national interests for the non-interaction in some cases. The methodological approach used in this study will be analytical-theoretical with some examples illustrating the (none) implementation in practice. The conclusions of this study are that multilateral diplomacy has shown success in certain issues for finding global solutions, but is not realized when the state interest has been in question.