We conceptualize the MNE as a portfolio of interdependent sub-units and examine its growth trajectory in relation to its existing portfolio. The empirical testing is based on a unique dataset that details all the location moves of US legal-services MNEs during 1949-2006. These MNEs evolve in directions that follow from their past. Their portfolios affect their subsequent moves, speaking for the impact of interdependencies among sub-units on the evolution of MNEs. The portfolio exercises stronger impact on entry than on exit, suggesting that different forces affect MNEs’ expansion and contraction. We outline strategic and organizational implications of the MNE as a portfolio.