Based on petrographic studies of the host rocks and metasomatites from the Kukurt scapolite deposit (Eastern Pamir), two stages of the development of metasomatic processes are revealed. The first, late-metamorphic stage, is subdivided into two, actinolite and hornblende-oligoclase, steps; the second, post-metamorphic stage, is subdivided into three steps: scapolite, albite, and chlorite-muscovite. According to the results of full silicate analyses of rocks by using the T. G. Petrov method of equal multiples, behavior of elements has been determined during the process of replacing quartz-biotite-amphibole-plagioclase schists by biotite-amphibole-scapolite metasomatites. Inert behavior was typical of Al and Si; Na was removed, and Ca, Ti, Mg, Fe, K, P, and Mn were supplied. The “Camebax” microanalyzer was used to determine chemical compositions of amphiboles, scapolites, and biotites from areal and veined scapolite metasomatites. Fluid microinclusions (two- and three-phase inclusions) were studied by homogenization in scapolite and quartz from late veined rocks. The results obtained show that the thermodynamic conditions of metasomatic processes of the second stage were as follows: T = 470–300 °C, P = 1000–400 bars.