➤ Strategies to conserve blood and reduce exposure to allogeneic blood improve outcomes after orthopaedic surgery.➤ A multidisciplinary team approach, including surgeons, anesthesiologists, hematologists, and other medical specialties, is required to deliver optimal blood management.➤ Key steps are to optimize preoperative hemoglobin levels, administer antifibrinolytics, use cell salvage for procedures with high blood loss, and adhere to restrictive transfusion thresholds.