Circulating tumor cells in lung cancer: cluster circulating tumor cells as hybrid epithelial-mesenchymal transition/mesenchymal-epithelial transition (E/M)

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Oct 2017Publisher:AME Publishing CompanyJournal:Journal of Thoracic Disease, volume 9, pages 3,547-3,550 (issn: 2072-1439, eissn: 2077-6624,

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Authors: Noriyoshi, Sawabata;

doi: 10.21037/jtd.2017.09.63

pmid: 29268338

pmc: PMC5723813

Circulating tumor cells in lung cancer: cluster circulating tumor cells as hybrid epithelial-mesenchymal transition/mesenchymal-epithelial transition (E/M)

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Abstract

Metastasis is the most frequent cause of death among lung cancer patients (1), as such it is crucial to understand the mechanism of cancer metastasis to control the disease. Almost all metastases rise from isolated tumor cells (ITCs) which are dislodged from the original cancer lesion.

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Nara Medical University
Japan

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