Wnt7a and miR-370-3p: new contributors to bladder cancer invasion

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Sep 2018Publisher:AME Publishing CompanyJournal:Biotarget, volume 2, pages 14-14 (eissn: 2522-669X,

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Authors: Danielle, Scheunemann; Anjan K, Pradhan; Swadesh K, Das; Devanand, Sarkar; Luni, Emdad; Paul B, Fisher;

doi: 10.21037/biotarget.2018.08.02

pmid: 31511849

pmc: PMC6738951

Wnt7a and miR-370-3p: new contributors to bladder cancer invasion

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Abstract

In eukaryotes, microRNAs (miRNAs) are central regulators of gene expression. These small noncoding RNAs are about 19–24 nucleotides long (1). miRNAs can silence gene expression by binding to a complementary sequence in the 3'-UTR of the target gene, which then triggers mRNA degradation.

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Virginia Commonwealth University
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Institute for Molecular Medicine
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VCU Massey Comprehensive Cancer Center
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