Right-sided infective endocarditis (RSIE) encompasses 5–10% of all infective endocarditis (IE) cases. Among them, about 90% involve the tricuspid valve (TV) (1). Major risk factors for TV infective endocarditis (TVIE) are intravenous drug use, pacemaker (PM) leads and indwelling vascular accesses (1,2). Only between 5–16% of RSIE cases require surgical intervention. Surgery for TVIE is indicated in the presence of TV vegetations >20 mm, decompensated right heart failure with severe tricuspid regurgitation (TR), recurrent pulmonary septic embolism and persistent bacteremia or sepsis due to aggressive and/or resistant microorganisms such as fungi and Staphylococcus aureus (3). Mortality of isolated TVIE is 0–15% (1). TV repair is the preferred surgical strategy; however, it is not always possible. This article presents the case of a patient with TVIE and focuses on the decision-making process and the TV operative techniques in the setting of TVIE.