There is no doubt that the business performance of the hotel enterprise depends upon the interrelationship of the hotel enterprise and the environment of the hotel industry in which the hotel operates. This environment provides the hotel enterprise with information crucial in guiding the hotel in its activities, thus helping to reduce the level of uncertainty and to improve the quality of strategic decisions. The specific or business environment shaped by the tourist market of the region will also impact on the performance of the hotel enterprise. One very popular interpretation of the enterprise-environment relationship is based on the model of natural selection, which has its roots in the biological theories o f the population evolution. This model focuses on a kind of natural selection according to Darwin’s theory of evolutionary adaptations. By accepting this theory, the hotel industry in our case would encourage only the survival of those hotel enterprises that are capable of adequately adjusting to changes. It should be pointed out that it would be extremely difficult to prepare a complete analogy of all the occurrences in the hotel industry with the theory of evolutionary adaptation. The hotel industry determines the critical success factors, which the hotel enterprise needs to embrace and apply in order to achieve high performance. Innovative hotel enterprises set about systematically combining their assets and their skills, which provides them with the individual competence needed to create and maintain a fairly long-term competitive advantage within their business environment and on the tourist markets. As a rule, it is the innovative hotel enterprise that creates the critical success factors which will become the standards of sound hotel business for all hotel enterprises of the region or country. By identifying the driving forces, it is possible to define the true top-priority strategic issues that need to be solved. These strategic issues can refer to maintaining or improving current strategic positions within the hotel industry or they can deal with selecting new areas of business i.e. new domestic or foreign tourist markets.