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Article . 2018 . Peer-reviewed
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Artriti olmayan Psoriasis Hastalarinda Kemik Mineral Yoğunluğunun Değerlendirilmesi

Authors: ŞAŞ, Senem; ERDOĞAN, Hilal Kaya; BULUR, İşıl;

Artriti olmayan Psoriasis Hastalarinda Kemik Mineral Yoğunluğunun Değerlendirilmesi

Abstract

In this study, weaimed to investigate the bone mineral density (BMD) of psoriasis patients,compare with healthy control group, and to evaluate whether topical corticosteroidsand systemic treatments affect BMD in psoriasis patients. Forty psoriasispatients admitted to dermatology outpatient clinic and 36 healthy subjects wereincluded in the study. Lumbar and femur BMD of patient and control groups weremeasured. No statisticallysignificant difference was found with regard to BMD in psoriasis and healthycontrol groups. When we compare the L1-L4 scores, femur BMD, L1-L4 BMD, femurZ, spine Z, and values of the psoriasis patients who receiving topical andsystemic treatments, we did not found statistically significant difference.Femur neck T score was significantly higher in the group receiving topicaltreatment than in the group receiving systemic treatment. There were notstatistically significant difference between disease duration and severity.TheL1-L4 scores, L1-L4 BMD, spine Z values did not differ significantly betweennail involvement and non-nail involvement groups. But the femur neck, femurtotal and femur Z scores were significantly lower in the group with nailinvolvement than group without nail involvement. This study shows that BMD of psoriasis patients is not differentfrom healthy control group.

Çalışmamızda eklem tutulumu olmayan psoriasishastalarında kemik mineral yoğunluğunu (KMY) değerlendirilerek sağlıklı kontrolgrubu ile karşılaştırmayı ve topikal kortikosteroid ve sistemik tedavi kullanımınınKMY üzerine etkisini göstermeyi amaçladık.Çalışmaya hastanemiz dermatoloji polikliniğine başvuran 40 psoriasishastası ve 36 sağlıklı gönüllü dahil edildi. Hasta ve kontrol grubunun lomberve femur KMY ölçüldü. Psoriazis ve sağlıklıkontrol gruplarında KMY açısından istatistiksel olarak anlamlı bir farkbulunmadı. Topikal ve sistemik tedavi alan psoriasisli hastaların L1-L4skorları, femur KMY, L1-L4 BMD, femur Z, omurga Z ve kalsiyum değerlerikarşılaştırıldığında, istatistiksel olarak anlamlı fark bulunmadı. Topikaltedavi alan grupta femur boynu T skoru, sistemik tedavi alan gruba göre anlamlıolarak daha yüksekti. Hastalık süresi veşiddeti arasında istatistiksel olarak anlamlı fark yoktu. L1-L4 skorları, L1-L4BMD, omurga Z, kalsiyum değerleri, tırnak tutulumu ve tırnak tutulumu olmayangruplar arasında anlamlı farklılık göstermedi. Ancak femur boynu, femur totalve femur Z skorları tırnak tutulumu olan grupta tırnak tutulumu olmayan grubagöre anlamlı olarak düşüktü.Buçalışma psoriasisli hastalarında, KMY’nin sağlıklı kontrol grubundan farklıolmadığını göstermektedir.

Country
Turkey
Keywords

Health Care Administration, kemik mineral yoğunluğu;osteoporoz;artrit;sedef, Sağlık Kurumları Yönetimi, psoriasis;arhritis;bone mineral density;osteoporosis

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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