Histologic Evidence for Impaired Growth Control in Diphenylhydantoin Gingival Overgrowth in Man Hassel, T. M., Page, R. C. and Lindhe, J. Arch Oral Biol 23: 381, May, 1978. To investigate the cellular and extracellular composition of the diphenylhydantoin (DPH) induced overgrowth, 12 epileptic patients medicated with DPH and who manifested gingival enlargement of the fibrous type, were studied. A control group of age-matched nonepilep- tics with healthy gingiva and no exposure to DPH were studied. Sections of excised interdental papillae were stained and fibroblast nuclei present within a given mass, were counted. When analyzed by direct count, neither nuclear length nor number of nuclei per unit area of DPH enlarged gingival tissue differed from normal gingiva. The conclusions drawn were that there is no evidence of hypertrophy, hyperplasia, nor fibrosis but rather a gingival overgrowth of normal compositon. Departments of Pathology and Periodontics, and the Center for Research in Oral Biology, University of Washington, Schools of Medicine and Dentistry, Seattle, Wash 98195. Dr. Gary Galovic Retention and Plaque-Inhibiting Effect in Man of Chlorhexidine After Multiple Mouth Rinses and Retention and Release of Chlorhexidine After Toothbrushing With A Chlorhexidine Gel Bonesvoll, P. Arch Oral Biol 23: 295, No. 4, 1978. To study the retention of Chlorhexidine after multiple mouth rinses of varying concentrations and to relate the findings to the plaque- inhibiting effect of Chlorhexidine measured on short-term sucrose- stimulated plaque, Chlorhexidine retention was measured during 10 consecutive 15-second mouth rinses with 10 ml of 0.05, 0.10, 0.20%; and 20 ml of 0.05% chlorhexidine-digluconate. Retention of the drug in the mouth was increased by multiple mouth rinses and by increasing the rinsing volume or concentration. In the plaque-inhibition experiment, rinsing with 10 ml of a 15% sucrose solution every 2 hours increased the plaque. Retention after toothbrushing with a 1.0% chlor- hexidine-digluconate gel was the same as the retention after a 0.1% rinse. The release of Chlorhexidine into saliva during the following 24 hours followed the same pattern as observed earlier after Chlorhexidine mouth rinses. Retention varied greatly between subjects. Department of Physiology and Biochemistry, Dental Faculty, University of Oslo, Oslo, Norway. Dr. Yau-Fwu Huang A Complication of Orthodontic Therapy: Localized Facial Recession and Loss of Attached Gingiva Treated by Grafting Israel, H. Angle Orthod 48: 149, April, 1978. Frequently problems which in reality were mucogingival defects of missing attached gingiva, were formerly treated as frenai aberrations by frenectomy. Three cases were described to illustrate orthodontic patients with areas of loss of attached gingiva, gingival recession (gingival cleft), and muscle pull of the free gingival margin. The three patients were treated with free gingival grafts to create new attached gingiva. The purpose of the article was to help orthodontists become aware of the nature of the problems and current means of treatment. The goal of treatment suggested was to approximate tissue attachment as close as possible to the cementoenamel junction for aesthetics. Children's Medical Center, 1735 Chapel Street, Dayton, Ohio 45404. Dr. Larry Johnson