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Оценка биораспределения Ð¼Ð¾Ð½Ð¾ÐºÐ»Ð¾Ð½Ð°Ð»ÑŒÐ½Ñ‹Ñ Ð°Ð½Ñ‚Ð¸Ñ‚ÐµÐ» и пептидов, Ð¼ÐµÑ‡ÐµÐ½Ð½Ñ‹Ñ Ñ€Ð°Ð´Ð¸Ð¾Ð½ÑƒÐºÐ»Ð¸Ð´Ð°Ð¼Ð¸, для расчета Ð¿Ð¾Ð³Ð»Ð¾Ñ‰ÐµÐ½Ð½Ñ‹Ñ Ð´Ð¾Ð· в Ð¾Ñ€Ð³Ð°Ð½Ð°Ñ Ð¸ Ñ‚ÐºÐ°Ð½ÑÑ Ð¾Ñ€Ð³Ð°Ð½Ð¸Ð·Ð¼Ð°

выпускная квалификационная работа магистра

Оценка биораспределения Ð¼Ð¾Ð½Ð¾ÐºÐ»Ð¾Ð½Ð°Ð»ÑŒÐ½Ñ‹Ñ Ð°Ð½Ñ‚Ð¸Ñ‚ÐµÐ» и пептидов, Ð¼ÐµÑ‡ÐµÐ½Ð½Ñ‹Ñ Ñ€Ð°Ð´Ð¸Ð¾Ð½ÑƒÐºÐ»Ð¸Ð´Ð°Ð¼Ð¸, для расчета Ð¿Ð¾Ð³Ð»Ð¾Ñ‰ÐµÐ½Ð½Ñ‹Ñ Ð´Ð¾Ð· в Ð¾Ñ€Ð³Ð°Ð½Ð°Ñ Ð¸ Ñ‚ÐºÐ°Ð½ÑÑ Ð¾Ñ€Ð³Ð°Ð½Ð¸Ð·Ð¼Ð°

Abstract

Данная работа посвящена применению программного обеспечения IDAC-Dose 2.1 для точного плана лечения и безопасного обслуживания пациентов. Был проведен анализ литературных источников биспецифических моноклональных антител. Описаны основные особенности биспецифических антител и его взаимодействий с Т-клетками. Указан краткий обзор фармпрепаратов из литературного источника. Описано программное обеспечение и алгоритмы его работы. Подробно описан ход исследования, проведена проверка и анализ результатов, сделаны выводы. В результате выявлены радиочувствительные органы и ткани пациентов.

This work focused on the use of IDAC-Dose 2.1 software for an accurate treatment plan and safe patient care. The analysis of literature sources of bispecific monoclonal antibodies was carried out. The main features of bispecific antibodies and its interactions with T cells are described. A brief overview of pharmaceuticals from a literary source is given. The software and algorithms for its operation are described. The progress of the study is described in detail, the results are checked and analyzed, and conclusions are drawn. As a result, the radiosensitive organs and tissues of the patients were identified.

Keywords

радионуклидная терапия, Ð‘Ð¸Ð¾Ñ‚ÐµÑ Ð½Ð¾Ð»Ð¾Ð³Ð¸Ñ, цирконий, поглощенные дозы., биспецифические антитела, биораспределение радиофарпрепаратов

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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Average
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