Targeting Rho Associated Kinases in Leukemia and Myeloproliferative Neoplasms

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 21 Sep 2012 English Publisher:Impact Journals, LLCJournal:Oncotarget, volume 3, pages 909-910 (eissn: 1949-2553,

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Authors: Raghuveer Singh, Mali; Reuben, Kapur;

doi: 10.18632/oncotarget.664

pmid: 23006984

pmc: PMC3660055

Targeting Rho Associated Kinases in Leukemia and Myeloproliferative Neoplasms

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Abstract

If ROCKs are going to be targeted as anti-leukemic agents either as a monotherapy or in combination with existing drugs, a better characterization of the relative contribution of ROCK1 and ROCK2 in disease progression is essential.

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Keywords

Isoenzymes, rho-Associated Kinases, Leukemia, Myeloproliferative Disorders, Humans, Molecular Targeted Therapy

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