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Oncotarget
Article . 2012 . Peer-reviewed
Data sources: Crossref
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Oncotarget
Article
License: CC BY
Data sources: UnpayWall
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Oncotarget
Other literature type . 2013
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Bruton's tyrosine kinase: oncotarget in myeloma

Authors: Yu-Tzu, Tai; Kenneth C, Anderson;

Bruton's tyrosine kinase: oncotarget in myeloma

Abstract

Our findings therefore provide a strong rationale for investigating Btk inhibitors in MM and WM to target both tumor cells and their supporting BM microenvironment and thereby both suppress tumor cell growth and abrogate MM-induced bone disease.

Keywords

Adenine, Cell Growth Processes, Protein-Tyrosine Kinases, Disease Models, Animal, Mice, Pyrimidines, Piperidines, Agammaglobulinaemia Tyrosine Kinase, Animals, Humans, Pyrazoles, Molecular Targeted Therapy, Waldenstrom Macroglobulinemia, Multiple Myeloma

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    24
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
24
Top 10%
Top 10%
Top 10%
gold
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