Novel Perylene-Based Antimicrobial PDI Chromophores

descriptionPublicationkeyboard_double_arrow_right Article 30 Aug 2023 Turkey Publisher:The Turkish Chemical SocietyJournal:Journal of the Turkish Chemical Society Section A: Chemistry, volume 10, pages 633-640 (eissn: 2149-0120,

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Authors: Cansu YILMAZ; Pınar GÜNER; Tülin AŞKUN; Funda YÜKRÜK;

doi: 10.18596/jotcsa.1292068

handle: 20.500.12462/13959

Novel Perylene-Based Antimicrobial PDI Chromophores

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Abstract

The main goal of the study was to monitor the Antimicrobial activity of two novel perylene diimides which were synthesized and characterized. Antimicrobial activity was investigated against Four Mycobacterium tuberculosis strains (MT) (Mt-H37Rv, Mt-H37Ra and two clinical isolates) and two Staphylococcus aureus strains [Methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus (SA)]. Minimum inhibitory concentrations (MICs) and minimum bactericidal activity (MBCs) were determined. Both compounds exhibited bactericidal effects and MICs were found to be changing in the range of 48-96 µg/mL for four MT-strains. Compounds were also effective on Staphylococcus strains at MIC = 96 µg/mL.

Country

Turkey

Related Organizations

Balıkesir University
Turkey
Balikesir University
Turkey

Keywords

MBC, Organic Chemistry, Methicillin Resistant, Perylene Diimide, Organik Kimya, Antimicrobial Activity, Perylene diimide;Antimicrobial activity;Mycobacterium tuberculosis;Methicillin resistant;Staphylococcus aureus;MIC;MBC, Staphylococcus Aureus, MIC, Mycobacterium Tuberculosis

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