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Intravitreal Methotrexate

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 25 Oct 2021Publisher:Knowledge E DMCCJournal:Journal of Ophthalmic and Vision Research, volume 16, pages 657-669 (issn: 2008-2010, eissn: 2008-322X,

Authors: Fatemeh Abdi; S. Saeed Mohammadi; Khalil Ghasemi Falavarjani;

doi: 10.18502/jovr.v16i4.9756

pmid: 34840688

pmc: PMC8593537

Intravitreal Methotrexate

- Summary
- Subjects
- Metrics

Abstract

Intravitreal methotrexate (MTX) has been proven to be an effective treatment for various intraocular diseases. In this article, a comprehensive review was performed on intravitreal applications of methotrexate. Different aspects of the administration of intravitreal MTX for various clinical conditions such as intraocular tumors, proliferative vitreoretinopathy, diabetic retinopathy, age-related macular degeneration, and uveitis were reviewed and the adverse effects of intravitreal injection of MTX were discussed. The most common indications are intraocular lymphoma and uveitis. Other applications remain challenging and more studies are needed to establish the role of intravitreal MTX in the management of ocular diseases.

Related Organizations

Guilan University of Medical Sciences
Iran (Islamic Republic of)
Iran University of Medical Sciences
Iran (Islamic Republic of)
Farabi Eye Hospital
Iran (Islamic Republic of)
Tehran University of Medical Sciences
Iran (Islamic Republic of)

Keywords

Ophthalmology, intraocular tumor, inflammation, proliferative vitreretinopathy, uveitis, intravitreal injection, Review Article, RE1-994, methotrexate

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	7
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average