Introduction: Tumors involving mandible are the most common cause of mandibulectomy due to their aggressive nature. Mandibulectomy is generally combined with adjunct treatment modalities like radiotherapy and chemotherapy to avoid high chances of recurrence. Many case reports of rehabilitation of mandibulectomy defects using poly methyl meth acrylate have been reported in the literature, but rehabilitation with cast partial denture along with salivary reservoir is scarce/ not reported. The patient chief complaint was difficulty in chewing food and dryness of mouth. Intra oral examination revealed missing alveolar ridge with corresponding teeth following mandibulectomy along with dryness of mouth. The contralateral side had good occlusion with no deviation of the mandible on opening or closing. Following the surgery, for Chondrosarcoma, patient had reported to our department for rehabilitation. The mandibulectomy defect was Cantor and Curtis Type III defect with xerostomia. Conclusion: The hemi mandibulectomy defect was rehabilitated with sectional cast partial denture using semi precision attachments along with salivary reservoir to improve form, function, esthetics and phonetics including clinical symptom of xerostomia, thereby improving quality of life of the patient. Keywords: Mandibular defect, Xerostomia, Salivary reservoir, Semi precision attachments, Cast partial denture.