
This review considers the stages of the development of synthetic peptide vaccines against infectious agents, novel approaches and technologies employed in this process, including bioinformatics, genomics, proteomics, large-scale peptide synthesis, high-throughput screening methods, the use of transgenic animals for modelling human infections. An important role for the development and selection of efficient adjuvants for peptide immunogens is noted. Examples of synthetic peptide vaccine developments against three infectious diseases (malaria, hepatitis C, and foot-and-mouth disease) are given.
Viral Hepatitis Vaccines, Vaccines, Synthetic, Hepatitis C, Malaria, Animals, Genetically Modified, Foot-and-Mouth Disease, Malaria Vaccines, Animals, Humans, Peptides
Viral Hepatitis Vaccines, Vaccines, Synthetic, Hepatitis C, Malaria, Animals, Genetically Modified, Foot-and-Mouth Disease, Malaria Vaccines, Animals, Humans, Peptides
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 33 | |
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| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Top 10% | |
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