Analysis of the immediate results of cystectomy in 159 patients showed that, in order to prevent peritonitis after cystectomy with ureterocoloanastomosis, it is advisable to combine intraoperative novocaine blockade of the nervous intermesenteric tract with ureter transplantation into the sigmoid part of the intestine below the sacro-lumbar joint or into the rectum, the rectum. In operations of bladder replacement with an intestinal graft (122 patients), a double-row uretero-intestinal anastomosis and suprapubic drainage of the intestinal reservoir are recommended. This significantly reduces the possibility of developing urinary peritonitis.