In July 1822, by the corresponding decree of the Emperor, the Yenisei Province was formed as part of five districts, and Krasnoyarsk was approved as the administrative center. According to the Revision of the Medical and Sanitary Law of September 07, 1913, five positions of county doctors were established in the Yenisei Province, which are entrusted with the performance of forensic and medical and police duties. However, women were not allowed to perform these duties. The atmosphere of professional relationships and issues of providing material, and scientific and informational content were revealed. From the article, we identified the persons who represented forensic medicine in the course of legal proceedings. Attention was drawn to the respectful attitude toward them and the high status of the civil service rank. Archival documents allowed us to compare the nature and completeness of the research conducted with modern requirements for expert documentation. The article contains photocopies of the original documents. The authors of the article provide an overview of the history of forensic medicine of the Yenisei Province based on the study and analysis of documents preserved in the State Archive of the Krasnoyarsk Region.