An epidemiological analysis of basic indices in obstetric aid in the Omsk region in comparison to nationwide data for 2007 to 2011 has been performed. There was identified unfavourable situation of reproductive and demographic characteristics - high incidence of extragenital morbidity in women, increasing the proportion of antenatal losses among as both term as preterm infants also, the prevalence of perinatal mortality in maternity institutions in districts, if compared with similar institutions in the city. There were determined main causes of stillbirth: certain conditions emerging in the perinatal period and intrauterine hypoxia, birth asphyxia. Low indices of neonatal health: a high level of prematurity, a number of infants with developmental retardation, and fetal hypoxia have been ascertained. The directions for improvement of the work of perinatal services in Russia have been suggested.