METHUOSIS AS AN EFFECTIVE ROUTE OF CELL DEATH IN ANTINEOPLASTIC THERAPY TARGETING SOLID TUMORS: A SCOPING REVIEW
METHUOSIS AS AN EFFECTIVE ROUTE OF CELL DEATH IN ANTINEOPLASTIC THERAPY TARGETING SOLID TUMORS: A SCOPING REVIEW
A morte celular é essencial à manutenção do funcionamento orgânico. A metuose é um tipo de morte celular do tipo não apoptótica, induzindo macropinocitose. Atualmente, vem sendo estudada sobre seus efeitos no câncer. Com base nisso, busca-se analisar os avanços no tratamento antineoplásico baseado em indução da metuose, identificando as neoplasias sólidas que estão sendo estudadas, as vias farmacológicas utilizadas pelas drogas e seus resultados in vitro e in vivo.
Macropinocytosis, Methuosis, Scoping review, Nasopharyngeal Carcinoma, Experimental Drugs, Prostate Cancer, Ewing Sarcoma, Lung Cancer, Triple-Negative Breast Cancer, Hepatocellular Carcinoma, Pharmacological Selectivity, Programmed Cell Death, Antineoplastic agent, Non-Apoptotic Cell Death, Pharmacological Pathways, Malignant Pleural Mesothelioma, Neoplasm, n Vitro and In Vivo Results, Glioblastoma, neoplasm
Macropinocytosis, Methuosis, Scoping review, Nasopharyngeal Carcinoma, Experimental Drugs, Prostate Cancer, Ewing Sarcoma, Lung Cancer, Triple-Negative Breast Cancer, Hepatocellular Carcinoma, Pharmacological Selectivity, Programmed Cell Death, Antineoplastic agent, Non-Apoptotic Cell Death, Pharmacological Pathways, Malignant Pleural Mesothelioma, Neoplasm, n Vitro and In Vivo Results, Glioblastoma, neoplasm
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