
doi: 10.17567/dfd.03808
Ozet Amac: Pleomerfik adenomlar tukruk bezlerinin benign tumorleridir. Duktal ve myoepitelyal hucrelerin karisimindan koken alirlar. Bu neoplasmlar farkli histolojik cesitlilige sahip olduklarindan miks tumor olarak adlandirilirlar. Pleomorfik adenomlar butun tukruk bezi tumorleri arasinda en sik rastlanilan tumor cesididir. Bu raporda klinik ve histopatolojik ozellikleri pleomrfik adenomayi gosteren 3 olguyu sunmayi amacladik. Olgular: Olgu 1: 29 yasindaki bayan hasta sert damaginin sol tarafinda bulunan sislik sikayetiyle Inonu Universitesi Dis hekimligi Fakultesi Agiz Dis Cene Cerrahisi Anabilim Dalina basvurdu. Hastanin muayenesinde kitlenin, asemptomatik, yavas buyuyen, nonulsere, 4.0-3.0 cm capinda oldugu goruldu. Insizyonel biyopsi sonucu kitleye pleomorfik adenom tanisi kondu. Lokal anestezi altinda kitle saglikli dokularida icine alacak sekilde eksize edildi. Histopatolojik olarak pleomorfik adenom teshisi konulan hastanin 1 yil takibinde rekurrens tespit edilmedi. Olgu 2: 61 yasindaki bayan hasta sol ust labial sulkusundaki sislik nedeniyle Inonu Universitesi Dis hekimligi Fakultesi Agiz Dis Cene Cerrahisi Anabilim Dalina basvurdu. Insizyonel biyopsi sonucu kitleye pleomorfik adenom tanisi kondu. Lokal anestezi altinda kitle diseke edilip cikarildi. 1 yillik takip suresi sonrasi rekurrens gozlenmedi. Olgu 3: 48 yasindaki erkek hasta Inonu Universitesi Dis hekimligi Fakultesi Agiz Dis Cene Cerrahisi Anabilim Dalina dis cekimi icin basvurdu. Yapilan klinik muayenede sert damaktaki sislik fark edildi. Insizyonel biyopsi sonucu kitleye pleomorfik adenom tanisi kondu. Genel anestezi altinda kitle eksize edildi.1 yillik takip suresi sonunda rekurrens gozlenmedi. Sonuc: Minor tukruk bezlerinde gorulen pleomorfik adenomlarin tedavisi genis lokal eksizyonla kitlenin cikarilmasidir. Enukleasyon yuksek rekurrens oranindan dolayi tavsiye edilmemektedir. Malign donusum riski ve ilk eksizyondan uzun yillar sonra bile rekkurrens gorulme ihtimali oldugu icin erken teshis, tedavi ve uzun takip periyodu pleomorfik adenom olgularinda onemlidir. Anahtar Kelimeler: Pleomorfik adenom, Sert damak, Dudak Abstract Aim: Pleomorphic adenomas are benign tumors of salivary glands that are derived from a mixture of ductal and myoepithelial cells. Because of their remarkable histological diversity, these neoplasms have also been called mixed tumors . Among all salivary gland tumors pleomorphic adenoma is the most common tumor. In this study we aimed to present clinical and histopathological features of 3 cases diagnosed as a Pleomorphic adenoma. Cases: Case1: A 29-year-old female patient was referred to the Inonu University Faculty of Dentistry Maxillofacial Surgery Department with the chief complaint of a swelling in the left side of the hard palate. On physical examination, a mass was palpated and it was asymptomatic, slow-growing, non-ulsere submucosal nodule with diameter 4.0–3.0 cm. An incisional biopsy was performed and under local anesthesia the mass was dissected and removed.. After 1 year follow-up there was no evidence of recurrence Case2: A 61 year old female patient was referred to the Inonu University Faculty of Dentistry Maxillofacial Surgery Department with a history of a painless lump in her upper left labial sulcus. After incisonal biopsy pleomorfic adenoma was diagnosed. Under local anesthesia the mass was dissected and removed. After 1 year follow-up there was no evidence of recurrence. Case3: A 48-year-old male patient was referred to the Inonu University Faculty of Dentistry Maxillofacial Surgery Department for tooth extraction. On clinical examination a painless lump was detected in his hard palate. After incisonal biopsy pleomorfic adenoma was diagnosed. Under general anesthesia the mass dissected and removed. After 1 year follow-up there was no evidence of recurrence. Result: The treatment of pleomorphic adenoma in minor salivary gland is wide local excision. Enucleation alone is not advisable because of the high rate of recurrence. Early diagnosis, treatment and long-term follow-up of PA are important because of the risk of malignant transformation and high risk of recurrence even several years after first excision. Key Words: Pleomorphic Adenoma; Hard Palate, Lip
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