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Hypohidrosis induced by topiramate in an adult patient

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2013Publisher:WileyJournal:Epileptic Disorders, volume 15, pages 203-206 (issn: 1294-9361, eissn: 1950-6945,

Authors: Alexandros Sarantopoulos; Styliani Karachristianou; George Georgiadis; Panagiota Boura; Evangelos Papamichalis;

doi: 10.1684/epd.2013.0568

pmid: 23773932

Hypohidrosis induced by topiramate in an adult patient

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Abstract

ABSTRACTHypohidrosis is an uncommon and reversible side effect of topiramate treatment, reported mainly in children. This report presents an adult patient with complex partial seizures who was treated with topiramate and developed hypohidrosis coupled with hyperthermia, related to high environmental temperature and physical exercise. Reduced sweat response was confirmed using the Neuropad test. Signs and symptoms ceased after drug discontinuation. During topiramate treatment, it is important to recognise this side effect, although the exact causal mechanism has not yet been clarified.

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Keywords

Adult, Hypohidrosis, Male, Epilepsy, Complex Partial, Fever, Topiramate, Humans, Anticonvulsants, Fructose

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	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	16
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%