
pmid: 21933755
ABSTRACTWe report the case of a patient with pharmacoresistant mesial temporal lobe epilepsy presenting psychomotor seizures with onset at early childhood. MRI showed a blurred internal structure of the right hippocampus and right mammillary body atrophy. Neuropsychological testing revealed deficits in selective attention and visual planning. Non‐invasive recording was not sufficient to precisely detect the seizure onset zone. Invasive recording showed seizure onset in the temporo‐polar neocortex, with spread to the amygdalum and hippocampus. A superselective resection of the temporal pole and amygdalum was performed with preservation of the hippocampus. Histology revealed the presence of focal cortical dysplasia (Palmini type Ib). Seizure frequency was reduced after surgery, and seizure freedom for two years was achieved with optimisation of the antiepileptic drug regime. Memory functions were preserved, and selective attention and visual planning improved following limited resection. This case suggests that, in selected cases, highly targeted resections with preservation of memory‐relevant structures may be the best choice considering both seizure control and unimpaired cognitive functioning.
Male, Intelligence, Brain, Electroencephalography, Middle Aged, Neuropsychological Tests, Amygdala, Anterior Temporal Lobectomy, Hippocampus, Neurosurgical Procedures, Temporal Lobe, Cognition, Treatment Outcome, Epilepsy, Temporal Lobe, Memory, Visual Perception, Humans, Anticonvulsants, Attention
Male, Intelligence, Brain, Electroencephalography, Middle Aged, Neuropsychological Tests, Amygdala, Anterior Temporal Lobectomy, Hippocampus, Neurosurgical Procedures, Temporal Lobe, Cognition, Treatment Outcome, Epilepsy, Temporal Lobe, Memory, Visual Perception, Humans, Anticonvulsants, Attention
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 1 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |
