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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Epileptic Disordersarrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Epileptic Disorders
Article . 2011 . Peer-reviewed
License: Wiley Online Library User Agreement
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Superselective anterior temporal resection in mesial temporal lobe epilepsy

Authors: Cordeiro, Joacir Graciolli; Wagner, Kathrin; Trippel, Michael; Zentner, Josef; Schulze-Bonhage, Andreas;

Superselective anterior temporal resection in mesial temporal lobe epilepsy

Abstract

ABSTRACTWe report the case of a patient with pharmacoresistant mesial temporal lobe epilepsy presenting psychomotor seizures with onset at early childhood. MRI showed a blurred internal structure of the right hippocampus and right mammillary body atrophy. Neuropsychological testing revealed deficits in selective attention and visual planning. Non‐invasive recording was not sufficient to precisely detect the seizure onset zone. Invasive recording showed seizure onset in the temporo‐polar neocortex, with spread to the amygdalum and hippocampus. A superselective resection of the temporal pole and amygdalum was performed with preservation of the hippocampus. Histology revealed the presence of focal cortical dysplasia (Palmini type Ib). Seizure frequency was reduced after surgery, and seizure freedom for two years was achieved with optimisation of the antiepileptic drug regime. Memory functions were preserved, and selective attention and visual planning improved following limited resection. This case suggests that, in selected cases, highly targeted resections with preservation of memory‐relevant structures may be the best choice considering both seizure control and unimpaired cognitive functioning.

Country
Germany
Keywords

Male, Intelligence, Brain, Electroencephalography, Middle Aged, Neuropsychological Tests, Amygdala, Anterior Temporal Lobectomy, Hippocampus, Neurosurgical Procedures, Temporal Lobe, Cognition, Treatment Outcome, Epilepsy, Temporal Lobe, Memory, Visual Perception, Humans, Anticonvulsants, Attention

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
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