Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is a rare benign disease characterized by persistent massive lymphadenopathy caused by increased numbers of macrophages within lymph node sinuses [1, 2]. These cells are often large and exhibit abnormal behaviour, engulfing intact cells (such as lymphocytes, erythrocytes, and plasma cells) into the cytoplasm, a phenomenon known as “emperipolesis”. Although the classic clinical presentation is painless [...]