Lymphoplasmacytic lymphoma is rare. Although most cases of LPL are Waldenström macroglobulinemia associated with an immunoglobulin M, there are exceptions. Indeed, few cases are immunoglobulin A-secreting or immunoglobulin G-secreting. These cases are poorly described and raise diagnostic difficulties. The purpose of this article is to describe an IgG lymphoplamacytic lymphoma case diagnosed recently in the hematology laboratory University Hospital of Toulouse.