Evaluating Human Embryonic Germ Cells: Concord and Conflict as Pluripotent Stem Cells
Copyright policy )Evaluating Human Embryonic Germ Cells: Concord and Conflict as Pluripotent Stem Cells
AbstractThe realization of cell replacement therapy derived from human pluripotent stem cells requires full knowledge of the starting cell types as well as their differentiated progeny. Alongside embryonic stem cells, embryonic germ cells (EGCs) are an alternative source of pluripotent stem cell. Since 1998, four groups have described the derivation of human EGCs. This review analyzes the progress on derivation, culture, and differentiation, drawing comparison with other pluripotent stem cell populations.
- University of Southampton United Kingdom
- Southampton General Hospital United Kingdom
- University of Salford United Kingdom
- University Hospital Southampton NHS Foundation Trust United Kingdom
Pluripotent Stem Cells, 570, Cell Culture Techniques, Cell- and Tissue-Based Therapy, 610, Mice, Cell Movement, Primordial germ cell, Animals, Humans, Growth Substances, Cell Proliferation, Stem cell, Gene Expression Profiling, Gene Expression Regulation, Developmental, Cell Differentiation, Gonad, Embryo, Mammalian, Culture Media, Germ Cells, Embryo, Embryonic germ cell, Human
Pluripotent Stem Cells, 570, Cell Culture Techniques, Cell- and Tissue-Based Therapy, 610, Mice, Cell Movement, Primordial germ cell, Animals, Humans, Growth Substances, Cell Proliferation, Stem cell, Gene Expression Profiling, Gene Expression Regulation, Developmental, Cell Differentiation, Gonad, Embryo, Mammalian, Culture Media, Germ Cells, Embryo, Embryonic germ cell, Human
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