Neurogenic regulation of renal circulation was studied by cross circulation experiments on mongrel dogs. The stimulation of the afferent cervical vagus nerve caused either pressor response with a decrease in renal blood flow or depressor response with an increase in renal blood flow. That of the afferent carotid sinus nerve elicited depressor response with an increase in renal blood flow. Intravenous injection of pressor agents to the recipient induced elevation of systemic blood pressure with an increase in renal blood flow. These results were consistent with an effect of baroreceptor reflex on the renal circulation. The splanchnicectomy abolished these reflex changes in the renal blood flow. The splanchnic nerves were the major reflex pathway of renal vasomotor control.