Langerhans cell histiocytosis
Copyright policy )Langerhans cell histiocytosis
The authors present a rare case of Langerhans cell histiocytosis in a 31 year old female patient with vulvar, peri-anal and oral lesions, diabetes insipidus, pulmonary skin and bone infiltrations. Skin biopsy immunohistochemistry presented positive S100 protein and vimentine, but the diagnosis was done with the demonstration of Birbeck granules with eletronic mucroscopy. The treatment was based on systemical chemotherapy although vulvar lesion has a bad response to chemotherapy.
- Jeonbuk National University Dental Hospital Korea (Republic of)
- Hospital Universitari Arnau de Vilanova Spain
- Institut Català de la Salut Spain
- UNIVERSIDADE DE SAO PAULO Brazil
- St. Jude Children's Research Hospital United States
Male, Adult, Adolescent, Diabetes insipidus, Cytoplasmic Granules, Langerhans cell, Recurrence, Multicenter Studies as Topic, Humans, Vimentin, Child, Aged, Randomized Controlled Trials as Topic, S100 Proteins, R, Middle Aged, Cytostatic Agents, Prognosis, Combined Modality Therapy, Clone Cells, Histiocytosis, Langerhans-Cell, Organ Specificity, Langerhans Cells, Histiocytosis X, Medicine, Cytokines, Drug Therapy, Combination, Female, Genital Diseases, Female, Diabetes Insipidus
Male, Adult, Adolescent, Diabetes insipidus, Cytoplasmic Granules, Langerhans cell, Recurrence, Multicenter Studies as Topic, Humans, Vimentin, Child, Aged, Randomized Controlled Trials as Topic, S100 Proteins, R, Middle Aged, Cytostatic Agents, Prognosis, Combined Modality Therapy, Clone Cells, Histiocytosis, Langerhans-Cell, Organ Specificity, Langerhans Cells, Histiocytosis X, Medicine, Cytokines, Drug Therapy, Combination, Female, Genital Diseases, Female, Diabetes Insipidus
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